ARK publishes a holdings file for each trading day that records how many shares each fund owns. The Shares Held column draws from these files: it displays today’s share count, and the number in parentheses shows the difference obtained by comparing today’s file with the previous trading day’s file.
| # | Date | Company | Ticker | CUSIP | Weight | Shares Held | Market Value |
|---|---|---|---|---|---|---|---|
| 1 | 09/30/2025 | TEMPUS AI INC | TEM | 88023B103 | 10.44% | 1,413,356 (-21,708) (-1.51%) | $111,047,380.92 |
| 2 | 09/30/2025 | CRISPR THERAPEUTICS AG | CRSP | H17182108 | 9.98% | 1,663,495 (-25,548) (-1.51%) | $106,081,076.15 |
| 3 | 09/30/2025 | TWIST BIOSCIENCE CORP | TWST | 90184D100 | 4.96% | 1,954,423 (-30,024) (-1.51%) | $52,769,421.00 |
| 4 | 09/30/2025 | RECURSION PHARMACEUTICALS-A | RXRX | 75629V104 | 4.90% | 10,609,660 (-163,008) (-1.51%) | $52,093,430.60 |
| 5 | 09/30/2025 | PERSONALIS INC | PSNL | 71535D106 | 4.48% | 7,494,374 (-115,140) (-1.51%) | $47,589,274.90 |
| 6 | 09/30/2025 | GUARDANT HEALTH INC | GH | 40131M109 | 4.41% | 756,799 (-11,628) (-1.51%) | $46,913,970.01 |
| 7 | 09/30/2025 | INTELLIA THERAPEUTICS INC | NTLA | 45826J105 | 4.24% | 2,663,900 (19,751) (0.75%) | $45,073,188.00 |
| 8 | 09/30/2025 | BEAM THERAPEUTICS INC | BEAM | 07373V105 | 4.12% | 1,834,430 (-28,176) (-1.51%) | $43,861,221.30 |
| 9 | 09/30/2025 | NATERA INC | NTRA | 632307104 | 4.06% | 264,719 (-4,056) (-1.51%) | $43,173,021.71 |
| 10 | 09/30/2025 | ADAPTIVE BIOTECHNOLOGIES | ADPT | 00650F109 | 3.80% | 3,005,606 (-46,176) (-1.51%) | $40,455,456.76 |
| 11 | 09/30/2025 | IONIS PHARMACEUTICALS INC | IONS | 462222100 | 3.60% | 597,412 (-9,168) (-1.51%) | $38,323,979.80 |
| 12 | 09/30/2025 | VERACYTE INC | VCYT | 92337F107 | 3.41% | 1,079,732 (-16,584) (-1.51%) | $36,289,792.52 |
| 13 | 09/30/2025 | SCHRODINGER INC | SDGR | 80810D103 | 3.35% | 1,778,127 (-27,312) (-1.51%) | $35,633,665.08 |
| 14 | 09/30/2025 | ARCTURUS THERAPEUTICS HOLDIN | ARCT UQ | 03969T109 | 3.14% | 1,775,334 (-27,276) (-1.51%) | $33,340,772.52 |
| 15 | 09/30/2025 | 10X GENOMICS INC-CLASS A | TXG | 88025U109 | 3.10% | 2,908,594 (-44,688) (-1.51%) | $32,983,455.96 |
| 16 | 09/30/2025 | ABSCI CORP | ABSI | 00091E109 | 3.02% | 10,808,750 (-166,068) (-1.51%) | $32,101,987.50 |
| 17 | 09/30/2025 | ILLUMINA INC | ILMN | 452327109 | 2.93% | 338,642 (-5,196) (-1.51%) | $31,111,040.54 |
| 18 | 09/30/2025 | CAREDX INC | CDNA | 14167L103 | 2.86% | 2,049,178 (-31,476) (-1.51%) | $30,450,785.08 |
| 19 | 09/30/2025 | PRIME MEDICINE INC | PRME | 74168J101 | 2.33% | 4,651,888 (-71,472) (-1.51%) | $24,748,044.16 |
| 20 | 09/30/2025 | 908 DEVICES INC | MASS | 65443P102 | 1.41% | 1,843,946 (-28,332) (-1.51%) | $15,028,159.90 |
| 21 | 09/30/2025 | NURIX THERAPEUTICS INC | NRIX | 67080M103 | 1.24% | 1,423,966 (-21,876) (-1.51%) | $13,214,404.48 |
| 22 | 09/30/2025 | PACIFIC BIOSCIENCES OF CALIF | PACB | 69404D108 | 1.19% | 10,122,116 (-155,520) (-1.51%) | $12,652,645.00 |
| 23 | 09/30/2025 | EXACT SCIENCES CORP | EXAS | 30063P105 | 1.17% | 232,572 (-3,564) (-1.51%) | $12,414,693.36 |
| 24 | 09/30/2025 | AMGEN INC | AMGN | 031162100 | 1.15% | 44,637 (-684) (-1.51%) | $12,229,198.89 |
| 25 | 09/30/2025 | COMPASS PATHWAYS PLC | CMPS | 20451W101 | 1.10% | 2,001,582 (-30,744) (-1.51%) | $11,749,286.34 |
| 26 | 09/30/2025 | INCYTE CORP | INCY | 45337C102 | 1.10% | 139,020 (-2,136) (-1.51%) | $11,662,387.80 |
| 27 | 09/30/2025 | BUTTERFLY NETWORK INC | BFLY | 124155102 | 1.07% | 5,812,440 (-89,304) (-1.51%) | $11,392,382.40 |
| 28 | 09/30/2025 | VEEVA SYSTEMS INC-CLASS A | VEEV | 922475108 | 1.05% | 38,260 (-576) (-1.48%) | $11,210,180.00 |
| 29 | 09/30/2025 | ATAI LIFE SCIENCES NV | ATAI | N0731H103 | 0.98% | 1,908,775 (-29,316) (-1.51%) | $10,402,823.75 |
| 30 | 09/30/2025 | QUANTUM-SI INC | QSI | 74765K105 | 0.94% | 7,214,128 (-110,844) (-1.51%) | $10,027,637.92 |
| 31 | 09/30/2025 | VERTEX PHARMACEUTICALS INC | VRTX | 92532F100 | 0.90% | 24,212 (-372) (-1.51%) | $9,571,245.72 |
| 32 | 09/30/2025 | CERUS CORP | CERS | 157085101 | 0.89% | 6,243,579 (-95,928) (-1.51%) | $9,490,240.08 |
| 33 | 09/30/2025 | GENEDX HOLDINGS CORP | WGS | 81663L200 | 0.66% | 61,683 (-936) (-1.49%) | $7,027,544.19 |
| 34 | 09/30/2025 | CARIS LIFE SCIENCES INC | CAI | 142152107 | 0.65% | 230,049 (-3,528) (-1.51%) | $6,901,470.00 |
| 35 | 09/30/2025 | REGENERON PHARMACEUTICALS | REGN | 75886F107 | 0.60% | 11,406 (-168) (-1.45%) | $6,395,914.50 |
| 36 | 09/30/2025 | GOLDMAN FS TRSY OBLIG INST 468 | X9USDGSFT | 0.40% | 4,264,854 (-322,043) (-7.02%) | $4,264,853.65 | |
| 37 | 09/30/2025 | STANDARD BIOTOOLS INC | LAB | 34385P108 | 0.34% | 2,858,631 (-43,920) (-1.51%) | $3,630,461.37 |
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